Contemporary Clinical and Economic Outcomes Among Oral Anticoagulant Treated and Untreated Elderly Patients With Atrial Fibrillation: Insights from the United States Medicare Database

by | Apr 28, 2022 | Cardiovascular, Publication

Abstract Background: Oral anticoagulants (OACs) mitigate the risk of stroke in atrial fibrillation (AF) patients. Objective: Elderly AF patients who were treated with OACs (apixaban, dabigatran, edoxaban, rivaroxaban, or warfarin) were compared against AF patients who...

Treatment persistence and maintenance dose titration among ulcerative colitis patients on biologics: A pooled study of three United States claims databases

by | Apr 28, 2022 | Gastrointestinal, immunology, Publication

Abstract Objective: This real-world study evaluated biologic treatment patterns in moderate-to-severe ulcerative colitis (UC) patients. Methods: IQVIA® PharMetrics®, IBM® MarketScan®, and Optum Clinformatics™ were pooled to identify UC patients with ≥1 claim for UC...

Treatment Patterns and Outcomes Before and After Humulin R U-500 Initiation Among US Patients with Type 2 Diabetes Previously Prescribed ≤200 Units/day of U-100 Insulin

by | Mar 3, 2022 | Endocrine, Publication

Abstract Introduction Humulin R U-500 (U-500R) utilization has increased in the past few years, raising concerns as U-500R is indicated only for patients requiring > 200 units of insulin. Thus, evidence of dispensed total daily dose (dTDD) > 200 units of prior...

Comparison of incidence/occurrence of cardiovascular events between ponatinib vs bosutinib among patients with at least one prior line of tyrosine kinase inhibitors in chronic myeloid leukemia in a community setting in the United States

by | Feb 22, 2022 | Cancer (blood), Publication

Authors: Levy M, Xie L, Wang Y, Neumann F, Srivastava S, Naranjo D, Xu J, Zhang Q, Dalal M Abstract Introduction: In this real-world study, the incidence of cardiovascular events (CV) including major adverse cardiac events (MACE), arterial occlusive events (AOE), and...