by Sandeep Gupta | Feb 16, 2023 | Endocrine, Publication
Abstract Aims To identify patient clusters with poor glucose control among type 2 diabetes mellitus (T2DM) patients with obesity who are receiving basal-bolus insulin and to identify the potential therapeutic inertia factors associated with poor control. Methods...
by Sandeep Gupta | Mar 3, 2022 | Endocrine, Publication
Abstract Introduction Humulin R U-500 (U-500R) utilization has increased in the past few years, raising concerns as U-500R is indicated only for patients requiring > 200 units of insulin. Thus, evidence of dispensed total daily dose (dTDD) > 200 units of prior...
by Sandeep Gupta | Nov 5, 2021 | Endocrine, Publication
Authors: Jieling Chen, Sujana Borra, Ludi Fan, Ahong Huang, Dhiren Patel, Rattan Juneja Abstract Introduction: A dedicated Humulin R U-500 (U-500R) prefilled disposable insulin pen (KwikPen) became available in 2016, yet limited evidence exists on...
by Sandeep Gupta | Jul 20, 2021 | Endocrine, Publication
Abstract Objectives: Severely insulin-resistant type 2 diabetes (T2D) patients face unique treatment challenges. Humulin R U-500 (U-500R) as insulin monotherapy with both basal/bolus properties addresses these challenges but remains understudied....
by Sandeep Gupta | May 7, 2020 | Cardiovascular, Endocrine, Publication
Abstract Authors: Gregory Y H Lip, Allison V Keshishian, Amiee L Kang, Xiaoyan Li, Amol D Dhamane, Xuemei Luo, Neeraja Balachander, Lisa Rosenblatt, Jack Mardekian, Anagha Nadkarni, Xianying Pan, Manuela Di Fusco, Alessandra B Garcia Reeves, Huseyin Yuce, Steven B...
by Sandeep Gupta | Jun 14, 2019 | Endocrine, Publication
Abstract Authors: Fang L Zhou, Charlie Nicholls, Lin Xie, Yuexi Wang, Neel Vaidya, Luigi F Meneghini Introduction: Type 2 diabetes (T2D) is characterized by worsening pancreatic β-cell function often requiring treatment escalation with oral antidiabetic drugs (OADs),...
