by [email protected] | Feb 14, 2023 | Cancer (blood), Hematology, Oncology, Publication
ABSTRACT Background: Primary myelofibrosis [PMF] is a myeloproliferative neoplasm associated with reduced overall survival (OS). Management strategies for PMF have evolved over the last two decades, including approval of ruxolitinib as the first Janus kinase 1...
by [email protected] | Feb 14, 2023 | immunology, Publication
Abstract Objective: Assess healthcare costs associated with systemic lupus erythematosus (SLE) flares among patients with and without lupus nephritis (LN). Methods: This retrospective cohort study used medical and pharmacy claims data from the United...
by [email protected] | Jan 13, 2023 | Cardiovascular, Publication
Abstract Background: In the USA, there is a steady rise of atrial fibrillation due to the aging population with increased morbidity. This study evaluated the risk of stroke/systemic embolism (S/SE) and major bleeding (MB) among elderly patients with...
by [email protected] | Dec 12, 2022 | Publication, Pulmonary
Abstract Background: Mycobacterium avium complex lung disease (MAC-LD) is an infection that is increasing in frequency, associated with substantial disease burden, and often refractory to treatment. Amikacin liposome inhalation suspension (ALIS) is the first therapy...
by [email protected] | Dec 9, 2022 | Publication, Pulmonary
Abstract BACKGROUND: Asthma is a common chronic respiratory disorder associated with significant disease and economic burden. Mepolizumab is an anti-IL-5 mAb approved for use as an add-on treatment in patients with severe eosinophilic asthma. OBJECTIVE: To assess the...
by [email protected] | Dec 9, 2022 | Cardiovascular, Publication
Abstract Background: Oral anticoagulants (OACs) mitigate stroke and systemic embolism (SE) risk in non-valvular atrial fibrillation (AF) patients but can increase the risk of major bleeding (MB). This study analyzed the gains in event-free time for these...